BLOOD GROUP PHENOTYPES

Alloantibodies causing haemolytic transfusion reactions or haemolytic disease in the fetus and newborn are dependent on the frequency with which alloantigens and alloantibodies occur.

Major Blood Group Phenotypes and their Frequencies (1–3)
No	Blood Group System [Symbol]	Phenotype	% Frequency	No	Blood Group System [Symbol]	Phenotype	% Frequency
001	ABO [ABO]	A1	29.7	014	Dombrock [DO]**	Do(a+b–)	18
		A2	9.3			Do(a–b+)	33
		B	11.4			Do(a+b+)	49
		O	46.1			Gy(a–)	Rare
		A1B	2.3	015	Colton	Co(a+b–)	92.0
		A2B	1.2			Co(a–b+)	0.2
002	MNS [MNS]	MMSS	6.0			Co(a+b+)	7.8
		MMss	9.1	016	Landsteiner-Wiener [LW]**	LW(a+b–)	97
		MMSs	14.4			LW(a–b+)	Rare
		MNSS	3.0			LW(a+b+)	3
		MNss	23.3	017	Chido/Rogers [CH/RG]**	Chido phenotype
		MNSs	22.7			CH/RG: 1,2,3	88.2
		NNSS	0.4			CH/RG: 1,–2,3	4.9
		NNss	15.6			CH/RG: 1,2,–3	3.1
		NNSs	5.5			CH/RG: –1,–2,–3	3.8
003	P [P]	P1+	74.8			CH/RG: –1,2,-3	Rare
		P1–	25.2			CH/RG: 1,–2,–3	Rare
004	Rh [RH]	See Rhesus phenotypes				Rodgers phenotype
005	Lutheran [LU]	Lu(a+b–)	0.2			CH/RG: 11,12	95
		Lu(a–b+)	92.3			CH/RG: 11,–12	3
		Lu(a+b+)	7.5			CH/RG: –11,–12	2
		Lu(a–b–)	Rare	018	H [H]	H	High incidence
006	Kell [KEL]	K– k+	90.9	019	Kx [XK]	Kx	High incidence
		K+ k–	0.4	020	Gerbich [GE]**	Ge:2,3,4	>99.9
		K+ k+	8.7			Ge:–2,3,4 (Yus type)	Rare
		Kp(a+b–)	<0 .1="" p="">			Ge:–2,–3,4 (Gerbich type)	Rare
		Kp(a–b+)	97.8			Ge:–2,–3,–4 (Leach)	Rare
		Kp(a+b+)	2.2	021	Cromer [CROM]	Cra, Tca, Dra, Esa	High Incidence
007	Lewis [LE]	Le(a+b–)	22.4			Tcb, Tcc, WESa	Low incidence
		Le(a–b+)	72.3	022	Knops [KN]**	Kn(a+b–)	94.5
		Le(a–b–)	5.3			Kn(a–b+)	1
008	Duffy [FY]	Fy(a+b–)	19.7			Kn(a+b+)	4.5
		Fy(a–b+)	32.7			McC(a+)	98
		Fy(a+b+)	47.6			Sl(a+)	98
009	Kidd [JK]	Jk(a+b–)	26.3			Yk(a+)	92
		Jk(a–b+)	23.6	023	Indian [IN]**	In(a+b–)	Rare
		Jk(a+b+)	50.1			In(a–b+)	99.9
010	Diego [DI]**	Di(a+b–)	<0 .01="" p="">			In(a+b+)	<0 .1="" td="">
		Di(a-b+)	>99.9	024	Ok [OK]**	Ok(a+)	100
		Di(a+b+)	<0 .1="" p="">			Ok(a–)	Rare
		Wr(a+)	<0 .1="" p="">	025	Raph [RAPH]	MER2
		Wr(b+)	High incidence	026	John Milton Hagen [JMH]	JMH	High incidence
011	Yt [YT]**	Yt(a+b–)	91.9	027	I [I]	I	High incidence
		Yt(a–b+)	0.3	028	Globoside [GLOB]	P	High incidence
		Yt(a+b+)	7.8	029	Gill [GIL]	GIL	High incidence
012	Xg [XG]**	Xg(a+)	Male         65.6 Female   88.7		Antigen Collections**	Csa  / Csb Vel / ABTI	95 / 34 Both >99
		Xg(a–)	Male         34.4 Female   11.3		Low incidence antigens (700 series)	By, Chra, Bi, Bxa, Pta, Rea etc.	<1 td="">
013	Scianna [SC]**	Sc:1,–2	99		High incidence antigens (901 series)	Lan, Ata, Jra, AnWj, Sda, Duclos etc.	>90
		Sc:–1,2	Rare
		Sc:1,2	1
		Sc:1,–2,Rd+	Rare
		Sc:1,2,Rd+	Rare
Note: Unless indicated, frequencies are based on blood group statistics of Australian blood donors; ** Frequency is based on Caucasian population.